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The uncondensed length of human DNA found in chromosomes is _______, whereas a typical cell is 10 µm in length.


A) 5 µm
B) 2 µm
C) 2 meters
D) 20 meters
E) 2.54 inches

F) A) and C)
G) B) and D)

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The structures that line up the chromatids on the equatorial plate during metaphase are called


A) asters.
B) polar and kinetochore microtubules.
C) centrosomes.
D) centrioles.
E) histones.

F) A) and E)
G) B) and E)

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B

An indicator of programmed cell death is


A) fragmented chromatin.
B) swelling of the membrane.
C) cell lysis.
D) loss of transcription control.
E) All of the above

F) A) and B)
G) A) and C)

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The _______ is the number, form, and type of chromosomes found in a cell.

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DNA damage by UV radiation causes the synthesis of


A) p53.
B) DNA.
C) Cdk.
D) cyclin.
E) p21.

F) D) and E)
G) A) and C)

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E

The total DNA content of each daughter cell is reduced during meiosis because


A) chromosomes do not replicate during the interphase preceding meiosis I.
B) chromosomes do not replicate between meiosis I and II.
C) half of the chromosomes from each gamete are lost during fertilization.
D) sister chromatids separate during anaphase of meiosis I.
E) chromosome arms are lost during crossing over.

F) A) and E)
G) None of the above

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The G2 phase always follows _______ phase.

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Homologous chromosomes undergo crossing over during


A) prophase I of mitosis.
B) prophase II of meiosis.
C) prophase I and II of meiosis.
D) prophase I of meiosis.
E) anaphase II of meiosis.

F) None of the above
G) D) and E)

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Down syndrome can be caused by an extra chromosome _______.

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Imagine that there is a mutation in the Cdk gene such that its gene product is nonfunctional. What kind of effect would this mutation have on a mature red blood cell?


A) The cyclin that bound to this Cdk would not be phosphorylated.
B) There would be no effect, because mature red blood cells do not enter the cell cycle.
C) The cell would be unable to replicate its DNA.
D) The cell would not be able to enter G1.
E) The cell would be unable to reproduce itself.

F) A) and B)
G) A) and C)

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Mature nerve cells, which are incapable of cell division, are most likely in


A) G1.
B) the S phase.
C) G2.
D) mitosis.
E) meiosis.

F) B) and D)
G) A) and E)

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A

How is cell division different in prokaryotic cells and eukaryotic cells?

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In most prokaryotic cells there is only ...

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Which of the following does not occur during mitotic prometaphase?


A) Disappearance of the nuclear envelope
B) Initial movement of chromosomes toward the equatorial plate
C) Adhesion of chromatids at the centromere
D) Synapsis of homologous chromosomes
E) Disappearance of the nuclei

F) None of the above
G) C) and E)

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In plant cells, cytokinesis is accomplished by the formation of a(n)


A) aster.
B) membrane furrow.
C) equatorial plate.
D) cell plate.
E) spindle.

F) A) and D)
G) A) and E)

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A chromatid is


A) a chromosome before it has undergone DNA replication.
B) one of the pairs of homologous chromosomes.
C) a homologous chromosome.
D) a newly replicated bacterial chromosome.
E) one-half of a newly replicated eukaryotic chromosome.

F) A) and C)
G) B) and E)

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DNA replication occurs


A) before both mitosis and meiosis.
B) only before mitosis.
C) only before meiosis.
D) during chromosome condensation.
E) during G2.

F) D) and E)
G) A) and E)

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The microtubules of the mitotic spindle attach to a specialized structure in the centromere region of each chromosome called the


A) kinetochore.
B) nucleosome.
C) equatorial plate.
D) aster.
E) centrosome.

F) All of the above
G) None of the above

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When cyclin binds Cdk,


A) the cell transitions from G2 to S.
B) kinase activation occurs.
C) chromosomes condense.
D) the cell quickly enters M phase.
E) the cell begins apoptosis.

F) None of the above
G) C) and D)

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The exchange of genetic material between chromatids on homologous chromosomes occurs during


A) interphase.
B) mitosis and meiosis.
C) prophase I.
D) anaphase I.
E) anaphase II.

F) C) and E)
G) B) and E)

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During prokaryotic cell division, two chromosomes separate from each other and distribute into the daughter cells by


A) attachment to microtubules.
B) a mitotic spindle.
C) repellent forces.
D) attachment to separating membrane regions.
E) All of the above

F) A) and C)
G) A) and B)

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