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Which of the following directly powers the ATP synthase?


A) carbohydrate metabolism
B) NADH/FADH2
C) the proton gradient
D) electron transfer

E) A) and B)
F) A) and C)

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During glycolysis, ATP is produced by oxidative phosphorylation.

A) True
B) False

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What is the fate of CoA after it delivers an acetyl group into the citric acid cycle?


A) It is used in protein synthesis.
B) It remains in an inactive form until the cell dies.
C) It is degraded and used for energy.
D) It is recharged with another acetate.

E) A) and B)
F) A) and D)

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Glycolysis can take place in the absence of which of the following small molecules?


A) FAD
B) ATP
C) NAD+
D) ADP

E) A) and B)
F) None of the above

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What are the functions of cytochrome c and ubiquinone?


A) They shuttle electrons between the protein complexes.
B) They synthesize water from molecular oxygen.
C) They translocate protons from the matrix to the inner mitochondrial space.
D) They produce ATP by substrate-level phosphorylation.

E) A) and C)
F) All of the above

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   Refer to the above illustration of a mitochondrion. Match the labelled parts of the mitochondrion with the steps of cellular respiration. A labelled part may be used once, more than once, or not at all. -oxidative phosphorylation A) outer mitochondrial membrane B) intermembrane compartment C) cytosol D) inner mitochondrial membrane E) matrix Refer to the above illustration of a mitochondrion. Match the labelled parts of the mitochondrion with the steps of cellular respiration. A labelled part may be used once, more than once, or not at all. -oxidative phosphorylation


A) outer mitochondrial membrane
B) intermembrane compartment
C) cytosol
D) inner mitochondrial membrane
E) matrix

F) A) and E)
G) C) and E)

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Which molecules are responsible for delivering the high-energy electrons from the citric acid cycle to the electron transfer system?


A) Cyt C and Q
B) NADH and Cyt C
C) FADH2 and Q
D) NADH and FADH2

E) A) and B)
F) None of the above

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If, during a chemical reaction, a molecule loses hydrogens, it could be described as being oxidized.

A) True
B) False

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   Refer to the above illustration of a mitochondrion. Match the labelled parts of the mitochondrion with the steps of cellular respiration. A labelled part may be used once, more than once, or not at all. -pyruvate oxidation A) outer mitochondrial membrane B) intermembrane compartment C) cytosol D) inner mitochondrial membrane E) matrix Refer to the above illustration of a mitochondrion. Match the labelled parts of the mitochondrion with the steps of cellular respiration. A labelled part may be used once, more than once, or not at all. -pyruvate oxidation


A) outer mitochondrial membrane
B) intermembrane compartment
C) cytosol
D) inner mitochondrial membrane
E) matrix

F) B) and C)
G) None of the above

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   Refer to the above illustration of a mitochondrion. Match the labelled parts of the mitochondrion with the steps of cellular respiration. A labelled part may be used once, more than once, or not at all. -ATP synthesis A) outer mitochondrial membrane B) intermembrane compartment C) cytosol D) inner mitochondrial membrane E) matrix Refer to the above illustration of a mitochondrion. Match the labelled parts of the mitochondrion with the steps of cellular respiration. A labelled part may be used once, more than once, or not at all. -ATP synthesis


A) outer mitochondrial membrane
B) intermembrane compartment
C) cytosol
D) inner mitochondrial membrane
E) matrix

F) All of the above
G) A) and B)

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Molecular oxygen is breathed in and expired as carbon dioxide.

A) True
B) False

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For every glucose molecule that goes through cellular respiration, how many times is a carbon molecule fully oxidized to CO2 in the citric acid cycle?


A) 4 times
B) 3 times
C) 2 times
D) 1 time

E) None of the above
F) C) and D)

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Which of the following molecules is responsible for carrying the acetyl group from pyruvate into the citric acid cycle?


A) FADH2
B) ATP
C) CoA
D) NADH

E) B) and C)
F) A) and B)

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What is the final product of glycolysis?


A) 1 molecule of pyruvate
B) 2 molecules of pyruvate
C) 1 molecule of glyceraldehyde-3-phosphate
D) 2 molecules of glyceraldehyde-3-phosphate

E) A) and B)
F) B) and C)

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What is the final product of glycolysis?


A) fructose
B) glyceraldehyde-3-phosphate
C) pyruvate
D) glucose

E) A) and B)
F) A) and C)

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The electrons that are present in NADH and FADH2 are very high energy and theoretically sufficient to produce ATP alone. Why then have biological systems evolved a way that uses the various steps of cellular respiration to produce ATP?


A) because steps in respiration allow for a controlled release of energy in small increments
B) because all living organisms must use oxygen and therefore must carry out cellular respiration
C) because it would be less efficient to produce ATP directly from NADH and FADH2
D) because the amount of ADP is insufficient to phosphorylate and make ATP

E) None of the above
F) A) and B)

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Which of the following processes actually produces a significant quantity of ATP?


A) pyruvate oxidation
B) glycolysis
C) oxidative phosphorylation
D) the citric acid cycle

E) A) and B)
F) B) and C)

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What is the proton-motive force used for?


A) diffusing substances across membranes and driving movement of flagella in bacteria
B) pumping substances across membranes and driving movement of flagella in eukaryotes
C) pumping substances across membranes and driving movement of flagella in bacteria
D) diffusing substances across membranes and driving movement of flagella in eukaryotes

E) None of the above
F) A) and D)

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Suppose that the pH of the matrix was significantly lower than the inner mitochondrial space. How would the ATP synthase function differently?


A) It would misfold.
B) It would no longer function properly.
C) It would require an ion to stabilize it.
D) It would hydrolyze ATP to form ADP.

E) A) and B)
F) All of the above

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In the process of aerobic metabolism, carbon-containing molecules are broken down. What is the energy from the electrons used for?


A) to generate a hydrogen ion gradient
B) to heat the organism in a cold environment
C) to alter enzyme structure
D) to directly supply the energy needs of an organism

E) None of the above
F) B) and D)

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