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Movement of the chromosomes during anaphase would be most affected by a drug that prevents ________.


A) nuclear envelope breakdown
B) cell-wall formation
C) elongation of microtubules
D) shortening of microtubules
E) formation of a cleavage furrow

F) All of the above
G) B) and D)

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Use the following information to answer the question(s) below. Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and, therefore, can be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times. -In eukaryotic cells, chromosomes are composed of ________.


A) DNA and RNA
B) DNA only
C) DNA and proteins
D) DNA and phospholipids

E) All of the above
F) A) and B)

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Use the data in the accompanying table to answer the following question(s) . -Of the following, the best conclusion concerning the difference between the S phases for beta and gamma is that ________.


A) gamma contains more DNA than beta
B) beta and gamma contain the same amount of DNA
C) beta cells reproduce asexually
D) beta are in the G0 phase
E) beta is a plant cell and gamma is an animal cell

F) B) and E)
G) A) and E)

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Myosin is a motor protein involved in animal cell cytokinesis. It binds to ATP or ADP, causing the myosin to move with respect to actin. What is the effect of the interaction between myosin and actin?


A) Vesicles containing plasma membrane constituents are transported to the metaphase plate, where cytokinesis takes place.
B) Excess cytoplasm is removed.
C) The cleavage furrow deepens.
D) Two new daughter nuclei form.

E) None of the above
F) A) and B)

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Use the data in the accompanying table to answer the following question(s) . -The best conclusion concerning delta is that the cells ________.


A) contain no DNA
B) contain no RNA
C) contain only one chromosome that is very short
D) are in the G0 phase
E) divide in the G1 phase

F) A) and B)
G) A) and C)

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The following question(s) are based on the accompanying figure. The following question(s)  are based on the accompanying figure.   -In the figure, at which of the numbered regions would you expect to find cells at metaphase? A)  I and IV B)  II only C)  III only D)  IV only E)  V only -In the figure, at which of the numbered regions would you expect to find cells at metaphase?


A) I and IV
B) II only
C) III only
D) IV only
E) V only

F) B) and D)
G) B) and C)

Correct Answer

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Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to ________.


A) disruption of mitotic spindle formation
B) inhibition of regulatory protein phosphorylation
C) suppression of cyclin production
D) myosin denaturation and inhibition of cleavage furrow formation
E) inhibition of DNA synthesis

F) D) and E)
G) A) and B)

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Through a microscope, you can see a cell plate beginning to develop across the middle of a cell and nuclei forming on either side of the cell plate. This cell is most likely ________.


A) an animal cell in the process of cytokinesis
B) a plant cell in the process of cytokinesis
C) an animal cell in the S phase of the cell cycle
D) a bacterial cell dividing
E) a plant cell in metaphase

F) B) and C)
G) A) and B)

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Which of the following are primarily responsible for cytokinesis in plant cells but not in animal cells?


A) kinetochores
B) Golgi-derived vesicles
C) actin and myosin
D) centrioles and centromeres
E) tubulin and dynein

F) B) and E)
G) A) and B)

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  -In the accompanying figure, MPF reaches its highest concentration during this stage. A)  I B)  II C)  III D)  IV E)  V -In the accompanying figure, MPF reaches its highest concentration during this stage.


A) I
B) II
C) III
D) IV
E) V

F) A) and D)
G) None of the above

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Kinetochore microtubules assist in the process of splitting centromeres by ________.


A) using motor proteins to split the centromere at specific arginine residues
B) creating tension by pulling toward opposite poles
C) sliding past each other like actin filaments
D) phosphorylating the centromere, thereby changing its conformation

E) A) and C)
F) A) and B)

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What happens if MPF (mitosis-promoting factor) is introduced into immature frog oocytes that are arrested in G2?


A) Nothing happens.
B) The cells undergo meiosis.
C) The cells enter mitosis.
D) Cell differentiation is triggered.

E) B) and D)
F) All of the above

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Scientists isolate cells in various phases of the cell cycle. They find a group of cells that have Scientists isolate cells in various phases of the cell cycle. They find a group of cells that have   times more DNA than G1 phase cells. The cells of this group are ________. A)  between the G1 and S phases in the cell cycle B)  in the G2 phase of the cell cycle C)  in the M phase of the cell cycle D)  in the S phase of the cell cycle times more DNA than G1 phase cells. The cells of this group are ________.


A) between the G1 and S phases in the cell cycle
B) in the G2 phase of the cell cycle
C) in the M phase of the cell cycle
D) in the S phase of the cell cycle

E) B) and C)
F) A) and D)

Correct Answer

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Which cytoskeletal proteins are important constituents of the contractile structures that form the cleavage furrows involved in animal cell cytokinesis?


A) actin
B) dynein
C) tubulin
D) myosin

E) B) and D)
F) C) and D)

Correct Answer

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At which phase are centrioles beginning to move apart in animal cells?


A) telophase
B) anaphase
C) prometaphase
D) metaphase
E) prophase

F) A) and C)
G) B) and D)

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In human and many other eukaryotic species' cells, the nuclear membrane has to disappear to permit ________.


A) cytokinesis
B) the attachment of microtubules to kinetochores
C) the splitting of the centrosomes
D) the disassembly of the nucleolus

E) A) and C)
F) A) and B)

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Which of the following does NOT occur during mitosis?


A) condensation of the chromosomes
B) replication of the DNA
C) separation of sister chromatids
D) spindle formation
E) separation of the spindle poles

F) A) and C)
G) C) and D)

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If there are 20 chromatids in a cell, how many centromeres are there?


A) 10
B) 20
C) 30
D) 40
E) 80

F) A) and B)
G) A) and C)

Correct Answer

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The following question(s) are based on the accompanying figure. The following question(s)  are based on the accompanying figure.   -In the figure, G1 is represented by which numbered part(s)  of the cycle? A)  I or V B)  II or IV C)  III only D)  IV only E)  V only -In the figure, G1 is represented by which numbered part(s) of the cycle?


A) I or V
B) II or IV
C) III only
D) IV only
E) V only

F) A) and C)
G) A) and E)

Correct Answer

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