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The filtration membrane consists of the


A) capillary epithelium, podocytes, and macula densa.
B) podocytes, basement membrane, and macula densa.
C) basement membrane, capillary epithelium, and macula densa.
D) parietal layer and visceral layer.
E) podocytes, capillary endothelium, and basement membrane.

F) A) and E)
G) All of the above

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Arrange the following structures in correct sequence: (1) ureter (2) renal pelvis (3) calyx (4) urinary bladder (5) urethra


A) 1, 2, 3, 4, 5
B) 3, 2, 1, 4, 5
C) 2, 4, 5, 3, 1
D) 3, 4, 1, 2, 5
E) 1, 3, 2, 4, 5

F) C) and D)
G) C) and E)

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Urine concentration and volume depend on water reabsorption in the


A) proximal convoluted tubule.
B) descending loop of Henle.
C) ascending loop of Henle.
D) distal convoluted tubule only.
E) distal convoluted tubule and collecting ducts.

F) A) and B)
G) A) and E)

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Filtrate reabsorption, which occurs regardless of the concentration and volume of urine produced, is referred to as


A) active.
B) obligatory.
C) facultative.
D) countercurrent.
E) nonessential.

F) A) and C)
G) C) and E)

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In which of the following locations is filtrate osmolality highest?


A) end of proximal convoluted tubule
B) tip of the loop of Henle
C) end of distal convoluted tubule
D) beginning of distal convoluted tubule
E) descending loop of Henle

F) B) and E)
G) All of the above

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Plasma contains a much greater concentration of _____ than the glomerular filtrate.


A) urea
B) water
C) protein
D) sodium ions
E) glucose

F) B) and E)
G) B) and D)

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Urine formation involves


A) filtration of the plasma.
B) reabsorption from the filtrate.
C) secretion into the filtrate.
D) production of red blood cells.
E) filtration of the plasma, reabsorption from the filtrate, and the secretion into the filtrate.

F) A) and E)
G) A) and D)

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The juxtaglomerular apparatus secretes


A) renin.
B) ADH.
C) oxytocin.
D) aldosterone.
E) angiotensin.

F) None of the above
G) C) and E)

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Tubular reabsorption and tubular secretion differ in that


A) tubular secretion is a passive process; tubular reabsorption uses active transport.
B) tubular secretion adds materials to the filtrate; tubular reabsorption removes materials from the filtrate.
C) tubular reabsorption increases urine volume; tubular secretion decreases urine volume.
D) tubular reabsorption occurs in Bowman's capsule; tubular secretion occurs in the peritubular capillary.
E) tubular secretion moves materials from the filtrate into the blood; tubular reabsorption moves materials from the blood into the filtrate.

F) D) and E)
G) A) and B)

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The proximal convoluted tubule is


A) lined with epithelial cells that lack microvilli.
B) the site of glucose and amino acid reabsorption.
C) permeable to water if ADH is present.
D) impermeable to water.
E) the site of water secretion.

F) A) and C)
G) A) and E)

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Which of the following events would increase filtration pressure?


A) increase in capsular pressure
B) constriction of the efferent arteriole
C) increase in colloid osmotic pressure
D) decrease in renal blood flow
E) dilation of the efferent arteriole

F) A) and B)
G) A) and C)

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If extracellular fluid osmolality is 385 mOsm/kg, the kidneys will increase reabsorption of


A) urea.
B) water.
C) sodium.
D) potassium.
E) chloride.

F) A) and B)
G) A) and C)

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Arrange the following in correct order. (1) cotransport molecule binds to sodium and glucose (2) establish sodium concentration gradient between tubular cells and tubular lumen (3) sodium and glucose moved into tubular cell (4) active transport of sodium from tubular cells to interstitial area


A) 2, 1, 3, 4
B) 4, 2, 1, 3
C) 1, 3, 4, 2
D) 2, 4, 1, 3
E) 1, 2, 3, 4

F) C) and E)
G) B) and E)

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Some lung cancers secrete large amounts of ADH. This causes increased water reabsorption in the


A) proximal convoluted tubule.
B) loop of Henle.
C) distal convoluted tubule and collecting ducts.
D) calyces.
E) urethra.

F) B) and D)
G) A) and B)

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Which of the following is between the proximal and distal convoluted tubules?


A) the glomerulus
B) the loop of Henle
C) the distal convoluted tubule
D) the proximal convoluted tubule
E) collecting duct

F) B) and E)
G) A) and B)

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The countercurrent multiplier system


A) is found in the collecting duct.
B) is assisted by hormones.
C) has fluid flowing in parallel tubes in opposite directions.
D) maintains the solute concentration of the medullary interstitial fluid.
E) has fluid flowing in parallel tubes in opposite directions and maintains the solute concentration of the medullary interstitial fluid.

F) C) and E)
G) D) and E)

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Substances that are cotransported into proximal convoluted tubule cells include


A) urea with water.
B) potassium with amino acids.
C) amino acids with bicarbonate ions.
D) glucose molecules with sodium ions.
E) chloride with potassium.

F) B) and E)
G) A) and E)

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All of the following are located in the renal cortex, except


A) collecting ducts.
B) renal corpuscles.
C) proximal convoluted tubules.
D) distal convoluted tubules.
E) afferent arteriole.

F) A) and B)
G) C) and D)

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Which of the following statements concerning the micturition reflex is false?


A) The micturition reflex is initiated by stretching the bladder wall.
B) Afferent signals are conducted to the sacral segments of the spinal cord by the pelvic nerves.
C) Efferent signals are sent to the bladder by sympathetic fibers in the pelvic nerve.
D) The micturition reflex usually produces a series of contractions of the urinary bladder.
E) The micturition reflex is modified by centers in the pons and cerebrum.

F) C) and E)
G) C) and D)

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Skeletal muscle that surrounds the urethra as it extends through the pelvic floor forms the


A) trigone.
B) lamina propria.
C) external urinary sphincter.
D) internal urinary sphincter.
E) involuntary portion of bladder control.

F) A) and B)
G) A) and C)

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